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Chikusetsusaponin IVa

CAS No. 51415-02-2

Chikusetsusaponin IVa( Calenduloside F )

Catalog No. M18699 CAS No. 51415-02-2

Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Chikusetsusaponin IVa
  • Note
    Research use only, not for human use.
  • Brief Description
    Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways.
  • Description
    Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used in T2DM patients.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Calenduloside F
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    AMPK
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    51415-02-2
  • Formula Weight
    794.98
  • Molecular Formula
    C42H66O14
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL 125.79 mM;
  • SMILES
    C[C@]12CC[C@@H](C([C@@H]1CC[C@@]1([C@@H]2CC=C2[C@]1(CC[C@@]1([C@H]2CC(CC1)(C)C)C(=O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C)(C)C)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)C(=O)O)O)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Li Y, ET AL. Chikusetsu saponin IVa regulates glucose uptake and fatty acid oxidation: implications in antihyperglycemic and hypolipidemic effects. J Pharm Pharmacol. 2015 Jul;67(7):997-1007.
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